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Decay of genetic variability in geographically structured populations.

机译:地理结构种群中遗传变异的衰减。

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摘要

The ultimate rate and pattern of approach to equilibrium of a diploid, monoecious population subdivided into a finite number of equal, large, panmictic colonies are calculated. The analysis is restricted to a single locus in the absence of selection, and every mutant is assumed to be new to the population. It is supposed that either the time-independent backward migration pattern is symmetric in the sense that the probability that an individual at position x migrated from y equals the probability that one at y migrated from x, or it depends only on displacements and not on initial and final positions. Generations are discrete and nonoverlapping. Asymptotically, the rate of convergence is approximately (I-u)2t[I-(2NT)-1]t, where u, NT, and t denote the mutation rate, total population size, and time in generations, respectively; the transient part of the probability that two homologous genes are the same allele is approximately independent of their spatial separation. Thus, in this respect the population behaves as if it were panmictic.
机译:计算了二倍体,单性群体再分为有限数量的相等的,大型的,panictic菌落的平衡的最终速率和方式。在没有选择的情况下,分析仅限于单个基因座,并且假定每个突变体都是新的种群。假设时间独立的向后迁移模式是对称的,即位置x上的一个人从y迁移的概率等于位置y上的一个人从x迁移的概率,或者它仅取决于位移,而不取决于初始值。和最终职位。世代是离散的且不重叠的。渐近地,收敛速度大约为(I-u)2t [I-(2NT)-1] t,其中u,NT和t分别表示突变率,总种群大小和世代时间;两个同源基因是同一等位基因的概率的瞬时部分与它们的空间间隔无关。因此,在这方面,人口的行为就好像是恐慌症一样。

著录项

  • 作者

    Nagylaki, T;

  • 作者单位
  • 年度 1977
  • 总页数
  • 原文格式 PDF
  • 正文语种 en
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